O'Connell K, Kinsella J, McMahon C, Holian J, O'Riordan S. Posterior reversible encephalopathy syndrome (PRES) associated with liquorice consumption. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Let's take a look at the forms, uses, and side effects of . Hsu, Y. L., Wu, L. Y., Hou, M. F., Tsai, E. M., Lee, J. N., Liang, H. L., Jong, Y. J., Hung, C. H., and Kuo, P. L. Glabridin, an isoflavan from licorice root, inhibits migration, invasion and angiogenesis of MDA-MB-231 human breast adenocarcinoma cells by inhibiting focal adhesion kinase/Rho signaling pathway. J Pharmacol Exp Ther 2006;316:1369-77. Aliment Pharmacol Ther 2004;20:1279-87. Phytother Res 2012;26(9):1381-1384. Amato P, Christophe S, Mellon PL. View abstract. View abstract. View abstract. This formula has also been shown to dramatically relieve various types of spasmodic pain such as muscle cramps in the back and legs (restless legs) stiff muscles premenstrual cramping sciatica and abdominal pain. Licorice can decrease potassium levels. Gardner Z, McGuffin M. Boca Raton, FL: CRC Press, 2013. Bardhan, K. D., Cumberland, D. C., Dixon, R. A., and Holdsworth, C. D. Clinical trial of deglycyrrhizinised liquorice in gastric ulcer. Because of its beneficial effects, the licorice root has been dubbed the "Medicinal plant of 2012." Now scientists have discovered that licorice root from the papilionaceae or leguminous family . J Assoc Physicians India 1989;37(10):647. A newly-filed federal lawsuit claims eating too much of The Hershey Company's Good & Plenty and black licorice Twizzlers candies can cause serious health problems, maybe even death. Kormann R, Languille E, Amiot HM, Hertig A. Li C, Wang ZB. View abstract. Moghadamnia, A. [Protective mechanism of Salvia miltiorrhiza and Paeonia lactiflora for experimental liver damage]. Licorice, tobacco chewing, and hypertension. View abstract. Amaryan G, Astvatsatryan V, Gabrielyan E, et al. Zhang YD, Lorenzo B, Reidenberg MM. Effect of preoperative licorice lozenges on incidence of postextubation cough and sore throat in smokers undergoing general anesthesia and endotracheal intubation. View abstract. J Endocrinol Invest 1996;19:624-9. The chemicals in licorice are thought to . "Water pills" can also decrease potassium levels. An Med Interna 1995;12(1):33-35. View abstract. Z., Zhang, Y. View abstract. View abstract. Paeoniflorin, a constituent of white peony root, has demonstrated inhibition of testosterone synthesis in vitro, without affecting estradiol synthesis.It reduces testosterone production by the ovaries but not the adrenal glands. View abstract. Effect of orally administered shao-yao-gan-cao-tang (Shakuyaku-kanzo-to) on muscle cramps in maintenance hemodialysis patients: a preliminary study. BMJ Case Rep. 2013 Sep 19;2013. View abstract. View abstract. For women taking oral contraceptives, there is a very small chance that this can counteract the effects of this medication. Zhongguo Zhong Xi Yi Jie He Za Zhi. [RETRACTED]. Tooth decay. Complement Ther Clin Pract. View abstract. Papandreou V, Magiatis P, Chinou I, et al. Armanini D, Lewicka S, Pratesi C, et al. Klin Wochenschr 1983;61:303-5. 6 Top Celery Juice Benefits & Side Effects. Br Med J 1971;3(773):501-503. Reuter, J., Merfort, I., and Schempp, C. M. Botanicals in dermatology: an evidence-based review. Oh, G. S., Pae, H. O., Choi, B. M., Lee, H. S., Kim, I. K., Yun, Y. G., Kim, J. D., and Chung, H. T. Penta-O-galloyl-beta-D-glucose inhibits phorbol myristate acetate-induced interleukin-8 [correction of intereukin-8] gene expression in human monocytic U937 cells through its inactivation of nuclear factor-kappaB. J Clin Pharm Ther 2002;27:229-30. . Intern Med 2007;46:575-8. Iran J Pharm Res 2012;11(2):541-8. Ed. Cureus 2020;12(11):e11656. View abstract. Biofactors 2009;35(1):98-104. 2014 Jun;20(6):516-20. Abe Y, Ueda T, Kato T, Kohli Y. Lower potassium levels can cause those abnormal heart arrhythmias. Cancer 1997;79(8):1494-1500. Mamgain RK, Gupta M, Mamgain P, et al. [Effect of dandi tablet on blood lipids and sex hormones in women of postmenopausal stage]. Hypertension encephalopathy after liquorice ingestion. Wang W, Tian DD, Zheng B, et al. Thom E and Wollan T. A controlled clinical study of kanjang mixture in the treatment of uncomplicated upper respiratory tract infections. J Clin Psychopharmacol 2008;28(3):264-370. Man SC, Li XB, Wang HH, et al. Pathogenetic considerations and presentation of a clinical case]. Fuhrman, B., Volkova, N., Kaplan, M., Presser, D., Attias, J., Hayek, T., and Aviram, M. Antiatherosclerotic effects of licorice extract supplementation on hypercholesterolemic patients: increased resistance of LDL to atherogenic modifications, reduced plasma lipid levels, and decreased systolic blood pressure. View abstract. A double-blind, randomized, placebo-controlled trial on the effects of an herbal preparation in patients with functional dyspepsia [Abstract]. Gibertoni, M., Bonito, V., Colombo, A., Falasca, A., and Nichelli, P. [Licorice-induced myopathy. View abstract. Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions. Heavy consumption of licorice during pregnancy has been associated with premature birth and health problems in the child. Taking licorice along with estrogen might decrease the effects of estrogen. Exp Clin Endocrinol Diabetes 2003;111:341-3. Evid Based Complement Alternat Med 2016;2016:8292486. Side effects, toxicity, and interactions. Chang GH, Lin YS, Hsu KH, et al. J Pharm Pharmacol 2003;55:1275-82. View abstract. This might increase the effects and side effects of methotrexate. Life Sci 2-23-2001;68(14):1687-1694. Jin, C. Y., Wang, D. L., and Fang, Z. D. [Effect of integrative Chinese and Western medicine in treating chronic urticaria and its impact on interleukin-10 and interleukin-8 in peripheral blood]. Am J Chin Med 2003;31:445-53. . The dogs treated with the herbal mixture saw a 37.5 percent improvement . [Paeonia Lactiflora injection in treating chronic cor pulmonale with pulmonary hypertension]. Clin Ter 1990;132(1):55-58. View abstract. Cureus 2021;13(7):e16454. Hawrelak, J. View abstract. Xu, L., Jiang, J., and Du, F. Z. Korri, H., Awada, A., Baajour, W., Beaini, M., and Nasreddine, W. [Rapidly progressing quadriparesis secondary to licorice (souss) intoxication]. and its bioactive compounds. Chen MF, Shimada F, Kato H, Yano S, Kanaoka M. Effect of glycyrrhizin on the pharmacokinetics of prednisolone following low dosage of prednisolone hemisuccinate. But, she survived . View abstract. therapy. Lipids Health Dis 2011;10:29. Pakravan F, Salehabad NH, Karimi F, Isfahani MN. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Koster, M. and David, G. K. Reversible severe hypertension due to licorice ingestion. Life Sci 1993;53(5):PL63-8. Because licorice has a hormone-like effect, it can relieve excessive gastric acid secretion. ['Licorice hypertension' also caused by licorice tea]. Botanical names: Paeonia lactiflora, Paeonia suffruticosa, Paeonia veitchii How It Works Peony contains a unique glycoside called paeoniflorin. 1. [Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis]. Yoshida S, Takayama Y. Licorice-induced hypokalemia as a treatable cause of dropped head syndrome. Peony (Paeonia spp). Qraa Advanced Lacto Dark Underarm Whitening Cream Product Claims Qraa underarm whitening cream claims to lighten dark underarms by reducing melanin from the skin in the area. View abstract. Features : Herbal Energy & Performance: Bronson's Korean Panax Ginseng provides 1000 MG per serving to naturally support energy and physical performance without any unwanted jitters. Yamashiki, M., Nishimura, A., Suzuki, H., Sakaguchi, S., and Kosaka, Y. Wong, A. L. and Chan, T. Y. Interaction between warfarin and the herbal product quilinggao. Exp.Mol.Med 12-31-2003;35(6):467-474. Removes excess melanin: Licorice extract brightens the skin in another way, too. 17. J Gastroenterol 1996;31(5):691-695. Jan. 13, 2020 Foods such as honey, licorice, oregano, and hot sauce have an antimicrobial effect and some of them trigger phage production in our gut. Paeonia lactiflora : Peony is another popular anti-androgenic herb. Fung AY, Look PC, Chong LY, et al. Peony-glycyrrhiza decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models. Neth J Med 2005;63:146-8. View abstract. Kang, D. G., Moon, M. K., Choi, D. H., Lee, J. K., Kwon, T. O., and Lee, H. S. Vasodilatory and anti-inflammatory effects of the 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) via a nitric oxide-cGMP pathway. Cancer Lett 12-10-2001;174(1):17-24. Li J, Fan X, Wang Q. Hypertensive crisis with 2 target organ impairment induced by glycyrrhizin: a case report. J Dermatolog Treat 2003;14(3):153-157. Efficacy of traditional Chinese herbal therapy in adult atopic dermatitis. View abstract. 2017 Apr 1;27(2):150-154. doi: 10.1684/ejd.2016.2946. Planta Med 1991;57(2):119-121. Note: Results may vary from person to person, depending on the skin type. Medically reviewed by Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT By Kirsten Nunez on October 16, 2020. View abstract. Potentiation of hydrocortisone activity in skin by glycyrrhetinic acid. View abstract. Yoon JY, Cha JM, Hong SS, et al. Mechanisms by which Hange-shashin-to reduces prostaglandin E2 levels. J Am Soc Nephrol 2002;13(1):191-196. J Neuroophthalmol. Effects of paeoniflorin on the cerebral infarction, behavioral and cognitive impairments at the chronic stage of transient middle cerebral artery occlusion in rats. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. When eaten in large quantities, black licorice can cause serious health issues. View abstract. Kim YR, Nam SH. Hsiu, S. L., Lin, Y. T., Wen, K. C., Hou, Y. C., and Chao, P. D. A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats. Select a condition to view a list of vitamins. Am J Chin Med 2003;31:445-53. . Zangooei Pourfard M, Mirmoosavi SJ, Beiraghi Toosi M, et al. Mol Cell Endocrinol. 1994;14:207-9, 195. . Dong quai grows at high altitudes in the cold, damp, mountains of China, Korea, and Japan. Visavadiya, N. P. and Narasimhacharya, A. V. Hypocholesterolaemic and antioxidant effects of Glycyrrhiza glabra (Linn) in rats. Fortschr.Med 7-30-1992;110(21):395-398. Eur J Pharmacol 11-7-2005;524(1-3):111-119. Comparative study of bioactive constituents in crude and processed Glycyrrhizae radix and their respective metabolic profiles in gastrointestinal tract in vitro by HPLC-DAD and HPLC-ESI/MS analyses. Eur Neurol 1992;32(1):44-51. Rikknen K, Seckl JR, Heinonen K, Pyhl R, Feldt K, Jones A, Pesonen AK, Phillips DI, Lahti J, Jrvenp AL, Eriksson JG, Matthews KA, Strandberg TE, Kajantie E. Maternal prenatal licorice consumption alters hypothalamic-pituitary-adrenocortical axis function in children. Int Endod.J 2011;44(1):51-58. 10. Biomed.Chromatogr. View abstract. Clinical and immunological consequences of total glucosides of paeony treatment in Sjgren's syndrome: A randomized controlled pilot trial. Licorice might increase how quickly the body breaks down paclitaxel. View abstract. The effect of a traditional Chinese prescription for a case of lung carcinoma. Sontia B, Mooney J, Gaudet L, Touyz RM. Du, J. H. and Dong, B. D. [Comparative study on clinical efficacy of using methotrexate singly or combined with total glucosides of Paeony in treating rheumatoid arthritis]. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. 2017;109:182-190. Life Sci 2005;78:413-20 . [Treatment of refractory polycystic ovary syndrome by bushen huoxue method combined with ultrasound-guided follicle aspiration]. Licorice root contains glycyrrhizin, which can cause side effects when eaten in large amounts. The sweet stuff in your kids' trick-or-treat buckets may come with a bitter side effect. Practitioner 1973;210:820-3. J Am Acad Dermatol 2011;65(4):699-714. The author has contributed to research in topic(s): Rheum officinale. Francini-Pesenti F, Puato M, Piccoli A, Brocadello F. Liquorice-induced hypokalaemia and water retention in the absence of hypertension. The 54-year-old man was in a fast food . O'Connell, R. L., White, I. R., White, J. M., and McFadden, J. P. Liquorice extract in a cosmetic product causing contact allergy. Further studies on the mechanism of the mineralocorticoid action of licorice in humans. An open study of 100 women with uterine fibroids showed that peony reduced the size of . Hyodo T, Taira T, Kumakura M, et al. View abstract. Yuan, H. N., Wang, C. Y., Sze, C. W., Tong, Y., Tan, Q. R., Feng, X. J., Liu, R. M., Zhang, J. 2020;2020:3727682. View abstract. Low doses of liquorice can induce hypertension encephalopathy. Effects of the licorice extract against tumor growth and cisplatin-induced toxicity in a mouse xenograft model of colon cancer. Phytother Res. A. View abstract. Hossain, M. S., Takimoto, H., Hamano, S., Yoshida, H., Ninomiya, T., Minamishima, Y., Kimura, G., and Nomoto, K. Protective effects of hochu-ekki-to, a Chinese traditional herbal medicine against murine cytomegalovirus infection. Armanini D, Bonanni G, Mattarello MJ, et al. J Clin Psychopharmacol 1997;17(3):234-235. Licorice-Induced Hypokalemia: A Case Report. View abstract. View abstract. The herb licorice may lower warfarin levels and can add to digoxin's effects. OTHER NAME(S): Bai Shao, Chi Shao, Chinese Peony, Common Peony, C. Peony (Paeonia lactiflora) is an herb. Other side effects of licorice use include . Pharm Biol. 2020. Clin Neurol Neurosurg 2003;105:286-7.. View abstract. View abstract. Am J Chin Med 1996;24:165-8. View abstract. Oh, G. S., Pae, H. O., Choi, B. M., Jeong, S., Oh, H., Oh, C. S., Rho, Y. D., Kim, D. H., Shin, M. K., and Chung, H. T. Inhibitory effects of the root cortex of Paeonia suffruticosa on interleukin-8 and macrophage chemoattractant protein-1 secretions in U937 cells. View abstract. Cai Y, Yuan Q, Xu K, et al. Int Immunopharmacol. Brasseur, A. and Ducobu, J. The treatment of human cancer with agents prepared from bovine cartilage. Effects of glycyrrhizin on biochemical tests in patients with chronic hepatitis -- double blind trial. View abstract. View abstract. Gender may affect the action of garlic oil on plasma cholesterol and glucose levels of normal subjects. . Shintani, S., Murase, H., Tsukagoshi, H., and Shiigai, T. Glycyrrhizin (licorice)-induced hypokalemic myopathy. (Doses up to 60 grams daily for up to 4 months have been used without reported adverse effects.) Crit Care 2011;15(1):R64. About Dr.Cope. Licorice root and white poney is a common herbal formula for PCOS originating in traditional Chinese medicine. View abstract. View abstract. View abstract. Hypokalemic paralysis due to licorice consumption is extremely rare, with only 40 cases in the English literature describing paralysis secondary to exposure to licorice in candies, medications, chewing tobacco, and herbal preparations. Chamberlain, J. J. and Abolnik, I. 1991;11(4):199-202, 195. View abstract. Ital J Neurol Sci 1983;4(4):493-497. 2020;16(3):458-462. Int Urol Nephrol. View abstract. View abstract. A comparison of carbenoxolone sodium and deglycyrrhizinated liquorice in the treatment of gastric ulcer in the ambulant patient. The biological compound pesticide is manufactured from the raw materials of Ailanthus altissima Swingle, Cyrtomium fortunei, geranium wilfordii, fructus forsythiae, Scutellaria baicalensis, gallnut, areca-nut, coconut shell, radix sophorae . Fiore, C., Eisenhut, M., Krausse, R., Ragazzi, E., Pellati, D., Armanini, D., and Bielenberg, J. Antiviral effects of Glycyrrhiza species. Messier, C., Epifano, F., Genovese, S., and Grenier, D. Licorice and its potential beneficial effects in common oro-dental diseases. Eur J Dermatol. Celery juice has become very popular now as it is believed to cure many health problems including obesity, thyroid, gout, blood pressure and fluid retention. Hyodo T, Taira T, Kumakura M, et al. Nihon Jinzo Gakkai Shi 2010;52(1):80-85. Wu, T. H., Chiu, T. Y., Tsai, J. S., Chen, C. Y., Chen, L. C., and Yang, L. L. Effectiveness of Taiwanese traditional herbal diet for pain management in terminal cancer patients. Combined Lifestyle and Herbal Medicine in Overweight Women with Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. J Cardiovasc.Surg (Torino) 2000;41(4):631-632. Effect of glycyrrhizin on the activity of CYP3A enzyme in humans. Postgrad Med J 2003;79:115-6.. View abstract. Part 182 -- Substances Generally Recognized As Safe. . Asl, M. N. and Hosseinzadeh, H. Review of pharmacological effects of Glycyrrhiza sp. View abstract. Foster CA, Church KS, Poddar M, Van Uum SH, Spaic T. Licorice-induced hypertension: a case of pseudohyperaldosteronism due to jelly bean ingestion. View abstract. Antiviral Res 1987;7(3):127-137. View abstract. J Altern Complement Med 2010;16(10):1065-1071. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. Paeonia lactiflora (Chinese peony) and Paeonia brownii (California peony) relax smooth muscle tissue with a particular affinity for the female reproductive tract. Warfarin is used to slow blood clotting. Sato H, Goto W, Yamamura J, et al. View abstract. Deglycyrrhizinated liquorice in aphthous ulcers. Int J Dermatol 1999;38:387-92 . QJM 2011;104(12):1093-1095. View abstract. Gao, X., Wang, W., Wei, S., and Li, W. [Review of pharmacological effects of Glycyrrhiza radix and its bioactive compounds]. View abstract. Zhongguo Zhong Xi Yi Jie He Za Zhi 2008;28(4):314-317. Eisenburg, J. Immediately afterwards, Teacher Liu looked at her, picked up her paper, and said, Student Zhou Xiaotong, this time I ll give you a warning. White Peony Tea Side Effects. [Clinical characteristics of five elderly patients with severe hypokalemia induced by glycyrrhizin derivatives]. Benge E, Shah P, Yamaguchi L, Josef V. Trick or Treat? Wang H, Dong L, Qu F, et al. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11. Although some people believe that peony tea is the tea with the lowest caffeine levels, actually peony tea has a high caffeine level, as much as 5%. Steinberg, D., Sgan-Cohen, H. D., Stabholz, A., Pizanty, S., Segal, R., and Sela, M. N. The anticariogenic activity of glycyrrhizin: preliminary clinical trials. J Hypertens 1985;3(1):19-23. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Lancet 2003;361:2045-6.. View abstract. [Clinical observation on auxiliary treatment of hormone dependence dermatitis by shufeng liangxue decoction]. 2016 Nov;48(11):1873-1880. doi: 10.1007/s11255-016-1345-5. [Study on activating blood and eliminating stasis of total paeony glycoside(TPG)]. Sheehan MP, Atherton DJ. Lorenzin, F., Degen, C., Milani, A., Siciliano, M., and Rossi, L. [Pseudo-hyperaldosteronism caused by licorice. WebMD does not provide medical advice, diagnosis or treatment. Sigurjonsdottir HA, Franzson L, Manhem K, et al. Russo S, Mastropasqua M, Mosetti MA, et al. Estrogenic and antiproliferative properties of glabridin from licorice in human breast cancer cells. Robles BJ, Sandoval AR, Dardon JD, Blas CA. View abstract. View abstract. J Clin Hypertens (Greenwich) 2008;10:153-7. View abstract. Mohire, N. C. and Yadav, A. V. Chitosan-based polyherbal toothpaste: as novel oral hygiene product. Tsuda T, Sugaya A, Ohguchi H, et al. Johns, C. Glycyrrhizic acid toxicity caused by consumption of licorice candy cigars. View abstract. Evid Based Complement Alternat Med 2016;2016:9852793. 2008;9(3):88-98. Little is known about whether it's safe to use licorice root while breastfeeding. Lin SH, Yang SS, Chau T, Halperin ML. Elinav E, Chajek-Shaul T. Licorice consumption causing severe hypokalemic paralysis. 2 in the perioperative stage of laparoscopic cholecystectomy]. Biol Pharm Bull. Postgrad Med 2017;129(3):329-31. Edelman ER, Butala NM, Avery LL, Lundquist AL, Dighe AS. Myopathies associated with red yeast rice and liquorice: spontaneous reports from the Italian Surveillance System of Natural Health Products. Postgrad Med J 1980;56(657):526-529. Gut 1969;10:299-302. View abstract. 44 ($0.09/Count) NEW PACKAGING White Peony Root Bai Shao 4oz 38. . We describe a patient who suffered life-threatening hypokalemic paralysis caused by consumption of licorice in the form of a tea sweetener superimposed on long . View abstract. Peony (Paeonia lactiflora) is an herb. Effects of mouthwash interventions on xerostomia and unstimulated whole saliva flow rate among hemodialysis patients: a randomized controlled study. Glycyrrhizin-Induced Pseudohyperaldosteronism: A Case Report. Volatiles with antimicrobial activity from the roots of Greek Paeonia taxa. View abstract. The roots are commonly used in Traditional Chinese Medicine (TCM) for many purposes. J Am Coll.Nutr 2007;26(3):209-218. Licorice, tobacco chewing, and hypertension. Bannister, B., Ginsburg, R., and Shneerson, J. Cardiac arrest due to liquoriceinduced hypokalaemia. Neurology 2010;75(21):1939-1941. View abstract. Licorice is available in many different types of products, including candies, lozenges, teas, chewing, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Side effects in people after breathing tube removal. View abstract. Phytother.Res. Chin Med J (Engl.) View abstract. View abstract. Stormer FC, Reistad R, Alexander J. Glycyrrhizic acid in liquorice - evaluation of health hazard. Eur J Pharm Sci. View abstract. Licorice is an herb that grows in parts of Europe and Asia. Cardiovasc.Drugs Ther 1998;12(6):599-600. Hum.Exp Toxicol. View abstract. Life Sci 9-27-2002;71(19):2267-2277. Licorice root and white peony for PCOS. Inhibition of 11 beta hydroxysteroid dehydrogenase obtained from guinea pig kidney by furosemide, naringenin and some other compounds. Fitoterapia 2004;75:45-9.. View abstract. Yorgun, H., Aksoy, H., Sendur, M. A., Ates, A. H., Kaya, E. B., Aytemir, K., and Oto, A. Brugada syndrome with aborted sudden cardiac death related to liquorice-induced hypokalemia. J Tradit.Chin Med 2010;30(1):47-50. View abstract. J Altern Complement Med. View abstract. Pharmacotherapeutic effects of toki-shakuyaku-san on leukorrhagia in young women. Although white peony is generally considered safe for most people, drinking large amounts might have some negative consequences. Dehours E, Vall B, Roug-Bugat ME, Florent B, Bounes V, Franchitto N. Suspected hypokalaemia following liquorice ingestion on board ship. Anesth Analg. Suzuki H, Ohta Y, Takino T, and et al. Am J Chin Med 1992;20(3-4):313-317. Licorice can decrease how quickly the body breaks down corticosteroids. Mitscher, L. A., Park, Y. H., Clark, D., and Beal, J. L. Antimicrobial agents from higher plants. Double-blind, placebo-controlled, randomized, pilot clinical trial of ImmunoGuard--a standardized fixed combination of Andrographis paniculata Nees, with Eleutherococcus senticosus Maxim, Schizandra chinensis Bail. Effect of licorice on reduction of body fat mass in healthy subjects.