OTHER NAME(S): Atomic number 38, Chlorure de Strontium, Chlorure, Strontium is a silvery metal found naturally as a non-radioactive element. 2013 Feb;98(2):592-601. doi: 10.1210/jc.2012-3048. Some research says that women with osteoporosis may not absorb strontium as they should. View abstract. View abstract. Sr can be found in Group 2 of the periodic table. Pearce, N. X., Addy, M., and Newcombe, R. G. Dentine hypersensitivity: a clinical trial to compare 2 strontium densensitizing toothpastes with a conventional fluoride toothpaste. Boron may be suitable for arthritis when taken in appropriate amounts. Review of clinical studies. View abstract. 5-3-2007;356(18):1809-1822. Results of Russian multicenter trial]. Osteoporos.Int. The efficacy of glucosamine sulfate in osteoarthritis: financial and nonfinancial conflict of interest. Cochrane Musculoskeletal Group. Sairanen S, Karkkainen M, Tahtela R, et al. Horm.Metab Res. In 2013, the committee of the European Medicines Agency (similar to the FDA in the United States) recommended suspending strontium ranelate (brand name Protelos/Osseor) for treating osteoporosis. (1) A radioactive form is even used as a form of cancer treatment for bone cancers andprostate cancer. Maheu E, Mazieres B, Valat JP, et al. The drug name for this radioactive form is Metastron. All rights reserved. Effects of long-term strontium ranelate treatment on vertebral fracture risk in postmenopausal women with osteoporosis. View abstract. Marie PJ, Ammann P, Boivin G, Rey C. Mechanisms of action and therapeutic potential of strontium in bone. View abstract. View abstract. J.Clin.Periodontol. It was recommended to my sister by her doctor. 5-10-2001;344(19):1434-1441. Scientific studies have shown that Sr may have positive effects on bone diseases like osteoporosis, bone cancer, prostate cancer, tooth sensitivity and tooth decay. O'Donnell, S., Cranney, A., Wells, G. A., Adachi, J. D., and Reginster, J. Y. Strontium ranelate for preventing and treating postmenopausal osteoporosis. Collins, J. F. and Perkins, L. Clinical evaluation of the effectiveness of three dentifrices in relieving dentin sensitivity. It's not known if strontium. View abstract. Connect with thousands of patients and caregivers for support and answers. Cochrane Database Syst Rev 2006;(4):CD005326. 1 Taking magnesium oxide with food can reduce stomach troubles. Strontium and calcium metabolism. This could cause the body to have too much strontium and potentially cause side effects. Bone 2009;45(3):460-465. View abstract. Meta-analysis: chondroitin for osteoarthritis of the knee or hip. The radioactive form of Sr is not available as a dietary supplement, but it is considered to likely be safe when administered by a health care professional by IV. J.Dent.Res. It seems to play a role in how your body makes new bone while it slows the breakdown of old bone. Blake, G. M., Zivanovic, M. A., McEwan, A. J., and Ackery, D. M. Sr-89 therapy: strontium kinetics in disseminated carcinoma of the prostate. View abstract. You also do not know whether they can seriously harm you. Cancer that has spread to bone and causes pain. It can be found in soil and seawater, and its actually used as a supplemental treatment for osteoporosis and other bone diseases. J.Bone Miner.Res. My wife has severe Osteoporosis .It has been improving with Medicines, Yearly injections , Exercise , Yoga .I think she is more benefitted by Walking in Sunlight abundunly available in India.Some resercah has been done by Ray Vio for Improving VitD UUsing LED lights of 293 nm wavelength.This will help .If Somebody has experience , pl share your experience.Thanks. A., Hoiseth, A., Felsenberg, D., Huss, H., Gilbride, J., Schimmer, R. C., and Delmas, P. D. Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis. Center for drug evaluation and research. Our team aims to be not only thorough with its research, but also objective and unbiased. If you are concerned about the bone-thinning disease osteoporosis, you may have heard about treatment with strontium. Biol.Trace Elem.Res. 1992;23(10):705-711. 2012. N Engl J Med 2004;350:504-6. Its a fancy word for the development of cavities! The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Cochrane Database Syst Rev 2005;(2):CD002946. A number of studies have shown that it can strengthen bone and reduce the risk of fractures, even among women 74 years of age or older when risks are highest. The typical diet includes 0.5 to 1.5 milligrams of strontium each day. There are many safe food sources and if you are not able to reach your daily calcium requirements through your diet, you may need a supplement. Chesnut III, C. H., Skag, A., Christiansen, C., Recker, R., Stakkestad, J. It's not known if strontium contained in dietary supplements has these effects. Lancet 12-7-1996;348(9041):1535-1541. 2007;19(4):330-333. View abstract. 2008;19(4):503-510. Reichenbach, S., Blank, S., Rutjes, A. W., Shang, A., King, E. A., Dieppe, P. A., Juni, P., and Trelle, S. Hylan versus hyaluronic acid for osteoarthritis of the knee: a systematic review and meta-analysis. Arch.Intern.Med. View abstract. Int.J.Rad.Appl.Instrum.B 1987;14(3):219-222. J.Clin.Dent. 1987;66(10):1518-1522. Osteoporos.Int. Scand J Rheumatol 2001;30(4):242-247. 2008;67(12):1736-1738. Periodontics. Addy, M., Mostafa, P., and Newcombe, R. G. Effect of plaque of five toothpastes used in the treatment of dentin hypersensitivity. J.Periodontol. Cheung, K. M., Lu, W. W., Luk, K. D., Wong, C. T., Chan, D., Shen, J. X., Qiu, G. X., Zheng, Z. M., Li, C. H., Liu, S. L., Chan, W. K., and Leong, J. C. Vertebroplasty by use of a strontium-containing bioactive bone cement. Health Phys 2004;86:193-6. They can decrease strontium absorption. Ozgur S, Sumer H, Kocoglu G. Rickets and soil strontium. Rizzoli R, Chapurlat RD, Laroche JM, et al. Skoryna SC. View abstract. It does this in two ways. A coordinator will follow up to see if Mayo Clinic is right for you. To avoid this interaction, take antacids at least two hours after taking strontium products. Reginster, J. Y., Lecart, M. P., Deroisy, R., and Lousberg, C. Strontium ranelate: a new paradigm in the treatment of osteoporosis. Metastron prescribing information. 2010;46(4):1038-1042. doi: 10.1016/j.bone.2009.12.006. Evaluation of symptomatic slow-acting drugs in osteoarthritis using the GRADE system. 2006;(2):CD005321. 1990;34(3):545-560. Arthritis Rheum 1998;41:81-91. View abstract. J Clin Endocrinol Metab 1966;26:566-72. 2006;54(11):3494-3507. View abstract. Strontium may also influence other essential functions, including calcium absorption, bone formation & breakdown, and it restores alkaline pH to improve the health of skin, hair, and nails). are clickable links to these studies. A consideration of the possible causes of dental hypersensitivity: treatment by a strontium-ion dentifrice. Protelos European Public Assessment Report, Scientific Discussion. [3] Bartl, R. & Bartl, C.The Osteoporosis Manual: Prevention. Modawal, A., Ferrer, M., Choi, H. K., and Castle, J. View abstract. View abstract. 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Human biokinetics of strontium--part II: Final data evaluation of intestinal absorption and urinary excretion of strontium in human subjects after stable tracer administration. How Well are You Living With Ankylosing Spondylitis? 5 Possible (and Controversial) Health Benefits, The Foods, Supplements & Oils to Increase Bone Healing, Daniel Fast: Benefits for Your Spiritual, Emotional and Physical Health, 15 Fermented Foods for a Healthy Gut and Overall Health, 9 Proven Black Seed Oil Benefits that Boost Your Health, L-Glutamine Benefits Leaky Gut & Metabolism, Chia Seeds Benefits: The Omega-3, Protein-Packed Superfood, Apple Cider Vinegar Benefits for Weight Loss, Skin Health, Cholesterol & More. Effects of oral supplementation with stable strontium. View abstract. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. Strontium(89) chloride versus palliative local field radiotherapy in patients with hormonal escaped prostate cancer: a phase III study of the European Organisation for Research and Treatment of Cancer, Genitourinary Group. Kidney Int. Therapeutic Research Faculty 2020. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. New treatment strategies: ipriflavone, strontium, vitamin D metabolites and analogs. Bone. Many formulas for bone health will include a form of Sr. 2010;21(2):42-48. The drug makes your bones stronger and lowers your chances of getting fractures. Medical studies done on the ingredients have shown conclusively that this product is effective. Bone 2001;28:446-53. In the mean time I do have bone density scans to keep an eye on bone density. View abstract. Its also used to create that alerting red color in emergency flares. 1992;71 Spec No:841-845. 1980;51(10):578-581. Osteoporos.Int. Effectiveness of desensitizing agents. Effects of strontium ranelate on spinal osteoarthritis progression. Its been compared to calcium in its bone-boosting abilities. 2006;3:CD005326. Doctors arent sure exactly how it works, but it seems to help the body make more bone and keep the bone you have from breaking down. Use strontium supplements with caution if you have kidney disease. Hunter House, 2014. Osteoporos.Int. Some antacids include calcium carbonate (Tums, others), dihydroxyaluminum sodium carbonate (Rolaids, others), magaldrate (Riopan), aluminum hydroxide (Amphojel), aluminum hydroxide/magnesium hydroxide combinations (Maalox, Mylanta), and others. Faith123 may be able to answer a question or two of yours about the reclast infusion treatment and her experience with it. View abstract. N.Engl.J.Med. (24, 25). Seeman, E., Devogelaer, J. P., Lorenc, R., Spector, T., Brixen, K., Balogh, A., Stucki, G., and Reginster, J. Y. Strontium ranelate reduces the risk of vertebral fractures in patients with osteopenia. View abstract. Please note the date of the last review on all articles. Strontium is a mineral and alkaline earth metal like calcium, and it seems to work similarly to calcium in the body with its main benefit being a boost to bone health. (12). These side effects may be mild or severe. Wang, C. T., Lin, J., Chang, C. J., Lin, Y. T., and Hou, S. M. Therapeutic effects of hyaluronic acid on osteoarthritis of the knee. Fed.Oper.Dent. Get answers to some of the most common questions about osteoporosis treatment. Br.J.Clin.Pharmacol. 12-15-2007;57(8):1410-1418. Strontium is a natural element. Although Sr-89 is mostly used when there are several painful metastatic sites, its application in earlier stages of the disease is beneficial, and it may decrease progression and the need for external radiotherapy. Over-the-counter dentifrices in the treatment of tooth hypersensitivity. A double-blind, randomized placebo-controlled trial published in The Journal of Clinical Endocrinology and Metabolism looked at the effects of Sr on 261 men with primary osteoporosis. View abstract. After you stop taking any of these bone-building medications, you generally will need to take another osteoporosis drug to maintain the new bone growth. Five years treatment with strontium ranelate reduces vertebral and nonvertebral fractures and increases the number and quality of remaining life-years in women over 80 years of age. Effects of strontium ranelate and alendronate on bone microstructure in women with osteoporosis. More Information For two years, 174 of the men received 2 grams of strontium ranelate per day while 87 men received a placebo. Is Lamb Healthy? View abstract. You may not realize it, but its possible that you have used, or are currently using, a toothpaste the contains strontium. Robinson RG, Preston DF, Schiefelbein M, Baxter KG. A new desensitizing dentifrice: preliminary report. Do not take it within 2 hours of ingesting calcium so I take it at bedtime. Recker R, Stakkestad J Weber T et al. Strontium citrate and strontium chloride are supplements and are not tested or regulated by the Food and Drug Administrations (FDA). Effects of long-term strontium ranelate treatment on the risk of nonvertebral and vertebral fractures in postmenopausal osteoporosis: Results of a five-year, randomized, placebo-controlled trial. View abstract. Symptomatic efficacy of avocado/soybean unsaponifiables in the treatment of osteoarthritis of the knee and hip: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial with a six-month treatment period and a two-month followup demonstrating a persistent effect. Gillam, D. G., Bulman, J. S., Jackson, R. J., and Newman, H. N. Comparison of 2 desensitizing dentifrices with a commercially available fluoride dentifrice in alleviating cervical dentine sensitivity. Tofu, firm, made with calcium sulfate, cup 253 mg per serving. Zhai, H., Hannon, W., Hahn, G. S., Pelosi, A., Harper, R. A., and Maibach, H. I. Strontium nitrate suppresses chemically-induced sensory irritation in humans. Strontium can attach to some antibiotics called quinolones in the stomach. Environ Sci Pollut Res Int 2021;28(18):23048-23059. 2007;18(12):1617-1624. 1978;49(5):269-272. @faith123, recently posted about having a second reclast infusion recently here, https://connect.mayoclinic.org/discussion/reclast-infusion/. 1977;95(5):982-985. View abstract. View abstract. Cottage cheese, 1% milk fat, 1 cup 138 mg per serving. I'm glad you found us. Kishore A, Mehrotra KK, Saimbi CS. View abstract. View abstract. A common therapeutic dose you will often seen recommended for boosting bone health is 680 milligrams per day. 1999;25(9):689-694. Sr-89 has been used as a form of treatment to manage pain resulting from bone pain due to cancer. Study design: Prospective animal model study. Any use of this site constitutes your agreement to the Terms of Use and Privacy Policy and Conditions of Use linked below. View abstract. However, I dont advocate using these supplements without first reviewing the precautions listed below and talking with your health care provider. View abstract. I wont name names, but some of the most well-known toothpastes for sensitive teeth include strontium in their formulas. 2011;22(8):2347-2355. View abstract. Barenholdt, O., Kolthoff, N., and Nielsen, S. P. Effect of long-term treatment with strontium ranelate on bone strontium content. That means it may affect how strong your bones are. The body needs zinc for the immune system to work properly. Oosterhof GO, Roberts JT, de Reijke TM, et al. Dose-dependent effects of strontium on osteoblast function and mineralization. Bolland, M. J., Grey, A. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators. View abstract. Rheumatology (Oxford). Strontium can attach to some antibiotics called tetracyclines in the stomach. Osteoporosis Int. Our team includes licensed nutritionists and dietitians, certified health education specialists, as well as certified strength and conditioning specialists, personal trainers and corrective exercise specialists. I was told by the endocrinologist who I went to for osteoporosis that AlgaeCal is no better than taking calcium and vitamin D. I am reading the book "Strong Women, Strong Bones" and I highly recommend it.